Music of the 1960's Essay Example | Topics and Well Written Essays - 750 words

Music of the 1960's - Essay Example As a result, the participants of war are always in need of encouragement, motivation, hope, and renewed courage to participate and sustain the struggle with a hope of winning at the long end. Music has always sought to provide these needs in parts or in totality. Indeed, music has been in the forefront to incite, condemn, and encourage people to war.  Moreover, war music acts as a vehicle to spread propaganda, incite people to participate, and as an incentive to patriotism and enlistment in the ranks (Wells, 2004). However, we also have anti-war songs that discourage participation in war and calls for its end. Indeed, music served as a catalyst to unite people against war and in particular, against the Vietnam War (Anderson, 2006).Hence, the significance of music in addressing the societal problem of war is unquestionable. This paper will address the issue of war using five songs recorded in the 1960s. To achieve this, the paper will analyze the songs for similarities and differenc es in how they address the social issue of war. The songs to consider include â€Å"Masters of War† by Bob Dylan, â€Å"For What It's Worth† by Buffalo Springfield,    â€Å"I Ain't Marching Anymore† by Ochs Phil, Phil Ochs â€Å"What Are You Fighting,† and Ccr â€Å"Bad Moon Rising.† All the five songs, advocate for anti-war activities with the main theme of ending war. Ccr â€Å"Bad Moon rising,† recognizes the fact that there is no need to fight claiming the war brings forth rage and ruin. Indeed, everyday that people go out for war, deaths are registered. Hence, the artist warns that the war front will claim lives. Hence, there is a need to stop the war. This is a roots rock song, whose target audience is the participants of war. English vocabularies feature in the lyrics. A group wrote and sang the song. Phil Ochs â€Å"What Are You Fighting† equally condemns fighting in that though we are fighting, many are jobless, no equalit y in our countries, the leaders are full of lies, the media is also practicing truancy, we are still enslaved, and children are in despair. Hence, before we venture into war we should win our wars at home. This is a folk song, whose target audience is the participants of war. English vocabularies feature in the lyrics. An individual singer wrote and sang the song. â€Å"For What It's Worth† by Buffalo Springfield, notes that a lot we go down if we continue fighting. Children will suffer, masses will die, and Paranoia  will strike deep. This is a folk rock song, whose target audience is everybody with war experiences. English vocabularies feature in the lyrics. The band wrote and sang the song. â€Å"I Ain't Marching Anymore† by Ochs Phil, Phil Ochs, sees no need to fight since the old leaders always leads the young to war  yet it is always the young that fall. Brothers and sisters have fallen to war, engaging in war for no good reason, enslaving many in war, cities destroyed, counties conquered and yet there is nothing positive to show though the war is still on. Indeed, it is time to stop the war. This is a folk song, whose target audience is nobody in particular. English vocabularies feature in the lyrics. An individual singer wrote and sang the song. â€Å"Masters of War† by Bob Dylan believes the world war will not end. The leaders and the rich lead the young to war and run away. They deceive them that the world war will be won yet millions are dying, property destroyed, children suffer

Compare between criminal law and civil law Essay

Compare between criminal law and civil law - Essay Example All through history, all social orders have had criminal codes for managing behavior .Democracies have constantly tried to change their fundamental standards and goals into achievable objectives through an arrangement of laws that adjust the privileges of people with the convincing needs of society in general. These objectives incorporate open request, residential peacefulness, and security of the fundamental privileges of people (White and Edward 19). The justice system works effectively when majority of individuals accept that the laws are sensible and that the system can work productively and viably. The issue of what laws ought to be endorsed regularly causes a serious debate. Members elected to represent the people often participate in enacting the laws of their people. Branches of government that ensure criminal laws are formulated and implemented include the executive, the judicial, and the legislative branch. Bahrains lawful framework is taking into account a blend of British Common Law, Islamic law, tribal law, and other common codes, regulations, and traditions (Cotran and Eugene 56). The constitution accommodates a supposedly free legal that has the privilege of legal audit; in any case, courts are liable to government weight in regards to verdicts, sentencing, and bids. Individuals from the law making family are members of the legal system and they participate in making the laws. Previously, the king and other senior government authorities have lost common arguments brought against them by private residents; notwithstanding, the judgments were not generally actualized speedily, if whatsoever. The constitution points out that the lord designates all judges by imperial announcement. The constitution does not give an authoritative extension affirmation process for legal nominees nor does it create an arraignment process Cotran and Eugene 63). The Bahrain criminal law is a type of Islamic law (Cotran and

Hemoglobin Malaria Haemoglobinopathies

Hemoglobin Malaria Haemoglobinopathies Despite major advances in the understanding of the molecular pathophysiology and control and management of the inherited disorders of hemoglobin (haemoglobinopathies), thousands of infants and children with this disease are dying. As a result in heterozygote advantage against malaria the inherited hemoglobin disorders are the commonest monogenic disease. Population migrations have ensured that haemoglobinopathies are now encountered in most countries including the UK. Haemoglobinopathies have spread from areas in the Mediterranean, Africa and Asia and are now endemic throughout Europe, the Americas and Australia. This review examines the available literature to find out more about the prevalence of haemoglobinopathies in the UK. The data on the demographics and prevalence of the gene variants of haemoglobinopathies was extracted from books, journals, reference sources, online databases and published review articles from the WHO. Introduction It has been estimated that approximately 7% of the world population are carriers of such disorders and that 3000 000 4000 000 babies with severe forms of haemoglobinopathies. Haemoglobinopathy disorders occur at their highest frequency in tropical regions and population migrations have ensured that they are now encountered in most countries. Because of this, haemoglobinopathies have become a global endemic, so the World Health Organization published journals and reviews with recommendations on screening programmes and management of haemoglobinopathies. The programmes are tailored to specific socioeconomic and cultural contexts and aimed at reducing the incidence, morbidity and mortality associated with these diseases. www.who.int/en/ The WHO Executive Board wrote a review on haemoglobinopathies. In this article, the WHO Executive Board recognized that the prevalence of haemoglobinopathies varies between communities, and that insufficiency of relevant epidemiological data may hamper effective and equitable management of haemoglobinopathies. On this note England implemented the LIVE programmes. The Executive Board also recognizes that haemoglobinopathies are not yet officially recognized as priorities in Public Health Sector. This raised an issue about awareness of haemoglobinopathies. The WHO Executive Boards advice for prevention and management of haemoglobinopathies was to design, implement and reinforce in a systematic equitable and effective manner, comprehensive national, integrated programs for prevention and management of haemoglobinopathies, including surveillance, dissemination, such programs being tailored to specific socioeconomic and cultural contexts and aimed at reducing the incidence, morbidity and mortality associated with these diseases. www.who.int/en/ With immigration in the UK on its highest, the prevalence of haemoglobinopathies is expected to increase. The NHS has implemented programmes for individuals with haemoglobinopathies by implementation of LIVE program (NHS Plan, 2000). LIVE program is set-up to implement variant screening in the whole of UK by the year 2007. LIVE program started as early as January 2004 in high prevalence. The NHS Trusts involved are to offer variant screening by end of 2004/5 (NHS Plan, 2000). Low prevalence Trust are expected to have implemented the screening program by January 2008 and so far 86 out of 90 Trusts have successfully implemented the program. Antenatal and Newborn Screening programs have compiled a training pack to assist Low Prevalence Trusts with the implementation of haemoglobinopathies screening programmes. The NHS Plan (2000) made a commitment to implement effective and appropriate screening programs for women and children including a new national linked Antenatal and Newborn screen ing programs for haemoglobinopathies. The NHS Plan (2000) recommends that all pregnant women living in high prevalence areas are offered screening for haemoglobinopathies. All pregnant women living in low prevalence areas are offered screening for haemoglobinopathies. If a woman is identified as being at increased risk using the family origin questionnaire, she will then be offered screening for haemoglobinopathies (NHS Plan, 2000). The Low Prevalence Trust is where the fetal prevalence of sickle cell disease is less than 1.5 per 10 000 pregnancies. Low prevalence trusts are to offer screening for variants based on an assessment of risk determine by a question to women about their babys fathers family origin by the end of 2005/6 (NHS Plan, 2000). Background on Haemoglobinopathies Haemoglobin: is the oxygen carrying capacity of the blood and it is also a protein. Haem is iron containing pigment, while globin is made up of chains which are a globular tetrameric protein which accounts for 97.4% of the mass of the haemoglobin molecule (Tortora et.al., 2006) . The globin tetramer consists of four polypeptides which are two alpha (ÃŽ ±) chains and two non-alpha chains. The synthesis of ÃŽ ¶ and ÃŽ µ chains is done during the first 10 to 12 weeks of fetal life. Within the fourth to the fifth week of intrauterine life ÃŽ ± and ÃŽ ² chains are synthesized. The non-alpha is beta (ÃŽ ²), gamma (ÃŽ ³), delta (ÃŽ ´), epsilon (ÃŽ µ) zeta (ÃŽ ¶) chains. Haemoglobin transports oxygen from the lungs to all parts of the body and it gives blood its red colour (Fleming, 1982) Haemoglobin synthesis Haem and globin synthesis occur separately but in a carefully coordinated fashion. Globin synthesis is under the genetic control of eight functional genes arranged in two clusters, the ÃŽ ± globin gene cluster on chromosome 16 and the ÃŽ ² globin gene cluster on chromosome 11. The major haemoglobin in the foetus is HbF (ÃŽ ±ÃŽ ²) 2 and in adults HbA (ÃŽ ±ÃŽ ²) 2 (Fleming, 1982). Haemoglobin Structure The primary structure of haemoglobin is made-up of amino acid sequence of globin. And the secondary structure comprise of nine non-helical sections joined by eight helices; tertiary structure describes globin chain folding to form a sphere and the quaternary structure of haemoglobin describes the tetrahedral arrangements of the four globin subunits ( Fleming, 1982). The external surface of each folded globin is hydrophilic and the inner surface is hydrophobic, this protects the haem from oxidation, which is also why each haem chain sits in a protective hydrophobic pocket. In haemoglobin A, ÃŽ ± ÃŽ ² dimmers are held together strongly at the ÃŽ ±1 ÃŽ ²1 or ÃŽ ±2ÃŽ ²2 junction. The tetramer is held together much less tightly at the ÃŽ ±1 ÃŽ ²2 and ÃŽ ±2 ÃŽ ²1 contact areas (Fleming, 1982). Haemoglobin function Each haemoglobin molecule can carry four oxygen molecules. Oxygenation and deoxygenation are accompanied by molecular expansion and contraction via haem haem interaction (Bienz, 2007). Under physiological conditions, blood in the aorta carries about 19.5ml of oxygen per 100ml of blood. Upon entering the tissues about 4.5ml of oxygen are donated per 100ml of blood. 2,3-DPG is an important modulator of haemoglobin A oxygen affinity in red cells (Fleming, 1982). Haemoglobin disorder (haemoglobinopathies) Haemoglobinopathies is a hematological disorder due to alteration of a genetically defect, that results in abnormal structure of one of the globin chains of the haemoglobin molecule (Bienz, 2007). Haemoglobinopathies are any of a group of diseases characterized by abnormalities, both quantitative and qualitative in the synthesis of haemoglobin (Hb) (Bienz, 2007). Qualitative affecting the quality of haemoglobin e.g. Sickle cell disorder and quantitative affecting the amount of haemoglobin produced e.g. Thalassaemias. Most of them are genetically inherited but occasionally they can be caused by a spontaneous mutation. Haemoglobinopathies are the worlds most common monogenic autonomic and recessive disease in humans (Anionwu et.al., 2001). 2.1Haemoglobinopathies fall into two main types; There are two categories of haemoglobinopathies. The two categories are: qualitative and quantitative; Qualitative affecting the quality of the haemoglobin e.g. Sickle cell disorder. In this disease the globin structure is abnormal. Quantitative the haemoglobin structure is normal but the amount of haemoglobin produced is affected. e.g. alpha and beta thalassaemias (Bienz, 2007). History of haemoglobinopathies In 1910 Herrick wrote an article in it he used the term â€Å"sickle† to describe the shape of the red blood cells of a 20 year old medical student from Grenada. This student had consulted Dr Herrick in 1994 complaining of a cough, fever and Feeling weak and dizzy. He constantly had anaemia episodes, jaundice, chest complications as well as recurring leg ulcers on both ankles. When his blood was examined, his red blood cells showed a large number of thin, elongated, sickle shaped and crescent- shaped forms (Herrick, 1990). The name thalassaemia was coined by the eminent haematologist George Whipple in 1936 as an alternative to the eponymous ‘Cooleys anaemia. He wanted a name that would convey the sense of an anaemia which is prevalent in the region of the Mediterranean Sea, since most of the early cases originated there. Thalassaemia is derived by contraction of thalassic anaemia (from the Greek thalassa -sea, an none and anemia blood) (Fleming,1982). Origins and Geographic distribution of haemoglobinopathies Carriers are found in all parts of the world: people from the North Mediterranean (South Europe) coast are 1-19% carriers. People of Arab origin are over 3% carriers. In Central Asia 4-10% and in South East Asia, the Indian subcontinent and China 1-40% carriers (the very high rates in this part of the world are due to HbE). In the Americas, North Europe, Australia and South Africa the local population has very low carrier rates but thalassaemia is still present because of the significant immigration from high prevalence area (Anionwu et.al.; 2001). Sickle cell and thalassaemia disorder mainly affect individual who are descended from families where one or more members originated from parts of the world where falciparum malaria was, or is still endemic. Population with such ancestry include those from many parts of Africa, the Caribbean the Mediterranean (including southern Italy, Northern Greece and Southern Turkey), Southeast Asia and thalassaemia gene is much wider now due to the hi storical movements of at-risk populations to North and South America, the Caribbean and Western Europe (Livingstone 1985). The geographic distribution of the thalassaemias overlaps with that of sickles cell disease. This is because carriage of these abnormal genes affords some protection against malaria. Thus, being heterozygous for one of these conditions offers a selective survival advantage and increases the opportunity for these genes to be passed on (Campbell et.al.,2004) 4Types and terminology of sickle cell and thalassaemia There are various types of sickle cell and thalassaemia disorders. The thalassaemia syndromes include alpha and beta thalassaemia major as well as beta thalassaemia intermedia. Sickle cell disorders (or Fickle cell disease include sickle cell anaemia (Hb SS), Sickle haemoglobin C disease (Hb SC) ÃŽ ² disease and E beta thalassaemia (www.sickle-thalassaemia.org/sickle.cel.htm) 4.1Sickle Cell Disorder: affects the normal oxygen carrying capacity of the red blood cells. The red blood cell forms a crescent or a sickled shape when it is deoxygenated. The ‘sickled cells are unable to pass freely through capillaries; the sickle cells also get stuck in blood vessels forming clusters which block the blood vessels and the blood flow. They dont last as long as normal, round red blood cells, which leads to anemia. This results in a lack of oxygen to the tissues in the affected area, resulting in hypoxia and pain (sickle cell crisis). Other symptoms include severe anaemia, damage to major organs and infection (NHS Antenatal and Newborn; 2006). There are several types of Sickle cell disease. The most common are: sickle cell anemia (SS), sickle hemoglobin C disease (SC), sickle beta plus thalassaemia and sickle beta zero thalassaemia. Each of these can cause pain episodes and complications. HbSS sickle is due to two sickle cell genes (â€Å"S†), one from each parent. This is commonly called sickle cell anemia. An individual with sickles cell anemia have a variation in the ÃŽ ²-chain gene, which then causes a change in the properties of hemoglobin which results in sickling of red blood cells (www.sickle-thalassaemia.org/sickle.cel.htm) HbSc inherited one sickle cell gene and one gene from an abnormal type of haemoglobin called â€Å"C†. It is due to the variation in the ÃŽ ²-chain gene. An individual with this variant suffers from mild chronic haemolytic anaemia. (NHS Antenatal and Newborn; 2006). HbS beta thalassaeamia: This form of sickle is due to inherited one sickle cell gene and one gene for beta. 4.2Thalassaemias: is a term used for the description of a globin gene disorders that results from a diminished rate of synthesis of one or more globin chains and a consequently reduced rate of synthesis of the haemoglobin or haemoglobins of which that chain constitutes a part ; ÃŽ ± thalassaemia indicates a reduced rate of synthesis of the ÃŽ ± globin chain, similarly, ÃŽ ², ÃŽ ´, ÃŽ ´ ÃŽ ² and ÃŽ µ ÃŽ ³ ÃŽ ´ ÃŽ ² thalassaemia indicate a reduced rate of synthesis of the h, ÃŽ ´, ÃŽ ´, +ÃŽ ² and ÃŽ µ + ÃŽ ³ + ÃŽ ´ + ÃŽ ² chains, respectively (Modell et.al, 2001). Thalassaemia is the most common single gene disorder known. It is autosomal recessive syndromes, which is divided into ÃŽ ±- and ÃŽ ² thalassaemia. Types of thalassaemia There are two types of thalassaemia: (i)Thalassaemia minor (thalassaemia trait) (ii)Thalassaemia major Thalassaemia minor is when a person inherits one thalassaemia gene, while thalassaemia major is a severe form of anaemia if a person inherits two thalassaemia genes, one from each parent (Bienz, 2007). Subtypes of thalassaemia Alpha (ÃŽ ±) thalassaemia results from inadequate production of ÃŽ ± chains, which are normally controlled by two pairs of chromosomes. If one or two are malfunctioning, then there is a healthy carrier state. If three are non- functional then anaemia results, known as HbH Disease, which can be quite severe but usually does not need blood transfusions and is compatible with a normal life span (Anionwu et al, 2001). If all four genes are non functional then the result is severe anaemia of the unborn child, leading to heart failure and death (miscarriage). This condition is known as hydrops felalis (Fleming, 1982). Beta (ÃŽ ²) Thalassaemia is caused by the bodys inability to produce normal haemoglobin, leading to a life threatening anaemia (Bienz, 2007). The severity of illness depends on whether one or both genes are affected and the nature of the abnormality. If both genes are affected, anemia can range from moderate to severe. Beta thalassaemia results from inadequate or lack of production of ÃŽ ² chains (Anionwu et.a.l, 2001). Homozygous, ÃŽ ² thalassaemia has two forms: major, in which the patient can survive only with regular transfusions of blood and intermedia in which the patient can survive with occasional or even with no transfusions at all. The condition requires frequent blood transfusions and treatment to prevent complications from iron overload, such as diabetes and other endocrine disorders (Anionwu et.a.l, 2001). Both of these conditions can restrict a child or adults ability to conduct their normal daily activities and can have profound psychological affects on individuals a nd their families This form of thalassaemia is the most important and constitutes a major public health problem in many parts of the world, because of the high frequency of carriers and the demanding treatment that must be followed (Fleming, 1985). Association of Haemoglobinopathies with Malaria Malariais a vector borne infectious disease caused by protozoan parasites. It is widespread in tropical and subtropical regions, including parts of the Americans, Mediterranean, Asia and Africa. It causes diseases in approximately 515 million people and kills between one and three million people, the majority of whom are young children. Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include symptoms of anemia (Campbell et al, 2004). Sickle cell developed as a by product of human defense mechanisms against malaria. The most severe form of malaria, falciparum malaria, leads to very high death rate in young infants. This is particularly a problem between the time immediately after birth, when they are protected by immunity from the mother, and the time when they are old enough to acquire their own immunity. Malaria is a parasite which lives within the red blood cells and feeds off the protein that is contained within those red cells, haemoglobin (Campbell et al, 2004). When the malarial parasite enters the blood stream through a mosquito bite, it penetrates the red blood cells by attaching to the outside membrane or envelope of the red blood cell and gaining entry (Franklin, 1990). Once in the red blood cell, the malarial parasites use the haemoglobin as a source of energy, so that they multiply within the red cells. The parasites multiple filling-up the red blood cells and once they are filled-up the red cells bur st, thereby releasing the multiple parasites in the blood. Each new young parasite enters a single cell again and multiplies again, thereby causing a disease or infection. Whenever the parasites burst out of the cells they cause illness and fever in patients. Malaria can be severe by causing death; death is believed to be caused by red cells not being able to pass through the narrow gaps in the smallest blood vessels and by blockage of tissues when so many parasites are in the red blood cell (Campbell et al, 2004). Over the years human genes developed ways to prevent malaria becoming serious and potentially lethal, the developments were to prevent malarial parasites from spreading and multiplying (Tortora et.al,2006). The most changes were changes (mutation) in the type of haemoglobin (haemoglobin S) within the red blood cell which would in turn slow down the multiplying of the parasite (Campbell et al, 2004). The individuals with haemoglobin S are known to have a sickle cell trait or being carriers of sickle cell haemoglobin. When sickle-cell haemoglobin has given up its oxygen in the cells, the red cells stick together to form crystalline groupings of haemoglobin known as polymers. The red blood cells become deformed into sickle shapes and the presence of these crystalline polymers within the red cells inhibits the growth of the malarial parasite (Beinz, 2007). Even though individuals with haemoglobin S stills suffer from malaria, they are protected from the most severe effects of malaria (Li vingstone, 1985). Diagnosis Diagnosis for sickle cell disease The most used diagnose test for sickle cell is the haemoglobin electrophoresis. HbS and HbC amino acid substitutions change the electrical charge of the protein, the migration pattern of the haemoglobin with electrophoresis or isoelectric focusing results in diagnostic patterns with each of the different haemoglobin variants. HbSBeta-thal requires careful evaluation of red blood cell count and mean corpuscular red cell volume (MCV) and specifically quantifying HbA, S, A2 and F. In emergency setting, the presence of HbS is detected using a five minute solubility test called sickledex. Sickledex test does not differentiate sickle syndromes from the benign carrier state (HbAS or a sickle trait (NHS Antenatal and Newborn; 2006). Diagnosis for thalassaemias When testing for thalassaemias, a blood test is the simplest and most effective test for diagnosis and also the use of a test called Haemoglobin Electrophoresis. The blood of individuals with thalassaemias tend to be microcytic (smaller in size) and hypochromic (paler in colour) (NHS Antenatal and Newborn; 2006). 7 Pathophysiology 7.1Sickle-cell Sickle-cell anemia is caused by changes (mutation) in the structure of the ÃŽ ² -globin chain of the haemoglobin replacing the amino acid glutamic acid with the less polar amino acid valine at the sixth position of the ÃŽ ² chain. When two wild type ÃŽ ±-globin subunits associate with two mutant ÃŽ ²-globin subunits forms hemoglobin S. Haemoglobin S polymerizes under low oxygen conditions, which causes distortion of red blood cells and also causes red blood cells to lose their elasticity, resulting in red blood cells forming an irreversible sickle shape (Fleming,1982). Very often a cycle occurs, as the cells sickle they cause a region of low oxygen concentration which causes more red blood cells to sickle. Repeated occurrence of sickling causes cells to not return to normal even when oxygen levels are normal. The deformation of cells makes it difficult for the cells to pass through capillaries resulting in vessel occlusion, severe anemia, ischemia and other problems (Beinz, 2007). 7.2Thalassaemias The pathophysiologic effects of the thalassaemias range from mild microcytosis to death in uterus. The anaemia manifestation of thalassaemia is microcytic hypochromic haemolytic anaemia (Belcher, 1993). The haemoglobin abnormality is caused by substitution of a single amino acid for another; or substitution of two amino acids, also amino acid deletion or fusion (point of mutation) and the synthesis of elongated chains. In alpha trait, one of the genes that form the alpha chain is defective (Beinz, 2007). In alpha-thalassaemia minor, two genes are defective and in haemoglobin H disorder, three genes are defective. Alpha-thalassaemia major is most fatal thalassaemia disorder; this is because four of the chains forming genes are defective. Without alpha chains, oxygen cannot be released to the tissues (Belcher, 1993). In beta-thalassaemia haemoglobin abnormality is due to the uncoupling of alpha and beta-chain synthesis. This causes a depression in beta-chain synthesis, resulting in er ythrocytes with a reduced amount of haemoglobin and accumulation of free alpha chains, which are unstable and easily precipitate the in cell (Bienz, 2007). 8.Causes Genetic control of haemoglobin synthesis The synthesis of structurally normal haemoglobin chains is determined by allelic genes situated on the autosomal chromosome (Beniz, 2007). Haemoglobinopathies occur due to an inheritance of one or more faulty copy of gene(s) that contain the information for the cells to make the globin chains. The gene may result in abnormality in the production or structure of the haemoglobin protein causing haemoglobinopathies (Franklin, 1990). Thalassaemia is an inherited autosomal recessive blood disorder. Genetic defects in Thalassaemia results in reduced synthesis of one of the globin chains which make up haemoglobin. Reduced synthesis of one of the globin chains causes the formation of abnormal haemoglobin molecules, which in turn causes anaemia. Anaemia is a symptom of the Thalassaemias. It is caused by under production of globin proteins, often through mutations in regulatory genes (Franklin, 1990). Inheritance of Haemoglobin Disorder Due to haemoglobin mutation, individuals who had haemoglobin trait had a resistance to dying from malaria, therefore passed on their haemoglobin trait gene to their children (Campbell et.al,2004). As time went on more individuals with the trait were born and eventually individuals who had haemoglobin trait had children together (Franklin, 1990). In that satiation (partnership), if both parents carry the trait gene, there is a one in four chance that any one child will receive the haemoglobin trait gene from one parent and also from the other, thereby having a haemoglobin disorder(Franklin, 1990) . Clinical Manifestations 9.1Thalassaemias clinical manifestations Individuals who inherited the alpha trait are usually asymptomatic, with possible mild microctyosis. Alpha- thalassaemia minor has signs and symptoms almost identical to those of beta-thalassaemia; mild microcytic hypochronic anemia, enlargement of the liver and spleen, and bone marrow hyperplasia (Belcher, 1993). Alpha- thalassaemia major cause hydrops fetalis and fulminana intrauterine congestive heart and liver, edema and massive ascites. The disorder usually is diagnosed post mortem (Bienz, 2007). Beta-thalassaemia minor causes mild to moderate microcytic-hypochronic anemia, mild splenomegaly, bronze coloring of the skin, and hyperplasia of the bone marrow. Skeletal changes depend on the degree of reticulocytosis, which in turn depends on the severity of the anaemia (Bienz, 2007). People who have beta-thalassaemia minor usually are asymptomatic, whereas those with beta- thalassaemia major the anemia is severe, resulting in a great cardiovascular burden, with high output congestive heart failure (Belcher, 1993). Blood transfusions can increase the persons life span by a decade or two. Individuals with beta-thalassaemia major have an enlarged liver and spleen, and growth and maturation are retarded (Belcher, 1993). A characteristic deformity develops on the face as the bones expand to accommodate hyperplastic marrow (Belcher, 1993). Both and beta thalassaemias major are life threatening. Children with thalassaemia major usually are week, fail to thrive, how poor development and experience cardiovascular compromise with high-output failure; if the condition goes untreated, these children die by 6 years of age (Modell et.al., 2001) Blood transfusions can return haemoglobin and hematocrit to normal levels, alleviating the anaemia induced cardiac failure. Iron overload and hemochromatosis, which are complications of transfusion therapy, are treated with chelating agents (Bienz, 2007). . 9.2.Sickle-cell clinical manifestations The severity of sickle cell disorder depends on the amount of haemoglobin S and the clinical manifestations, which are signs and symptoms of the individuals with sickle-cell (Belcher, 1993) . Manifestations of the sickling are those of hemolytic anemia; pallor, jaundice, fatigue and irritability. Extensive sickling can precipitate four types of crises: vaso-occlusive or thrombotic crises and a plastic crisis (Belcher, 1993). A vaso-occlusive crises begins with red blood cells sickling in the microcirculation. Vasospasm brings a log-jam effect causing blood flow to stop flowing in the vessels and this will lead to thrombosis (blood clot formation) and infarction of local tissue occur, resulting in ischemia, pain and organ damage (Modell et.al.,2001). Vaso-occlusive crisis is believed to be extremely painful and lasts an average of 4 to 6 days. This crisis may develop spontaneously or may be precipitated by localized hypoxemia (low PO2) exposure to cold, dehydration, acidosis (low pH), or infection. In infancy, sickle-cells first manifestation is the symmetric painful swelling of the hands (see Fig 3) and feet, but in older children and adults, the large joints and surrounding tissues become swollen and painful. Individuals with the sickle-cell disorder suffer from severe abdominal pain caused by infarction in abdominal structures (Belcher, 1993). Any cerebral vascular accidents may cause paralysis or othe r central nervous system deficits, and if penile veins are obstructed priapism may occur. Studies have shown that bone, especially weight- bearing bones, are also a common target of vaso-occlusive damage, this is due to bone ischemia (Bienz, 2007). The spleen of individuals with sickle-cell disorder is frequently affected due to its narrow vessels, functions in clearing defective red blood cells and this results in a sequestration crisis (Belcher,1993). A sequestration crises, is occurrence of large amounts of blood pool in the liver and spleen. It only occurs in young children and death results from cardiovascular collapse (NHS Antenatal and Newborn,2006). An aplastic crisis develops when a compensatory increase in erythropoiesis is compromised; this then results in profound anemia (Belcher,1993). A hyperhemolytic crisis is rare but may occur with certain drugs or infections. G-6-PD deficiency, when also present, contributes to this type of crisis (Belcher,1993). Clinical manifestations of sickle cell disease do not usually appear until an infant is at least 6 months old. The most cause of death in individuals with sickle-cell anemia is infections, but it is major problem at all ages. Infections are due to splenic dysfunction from sickle damage (Belcher,1993). This occurs from a few months of age especially with certain bacteria e.g. pneumococcal sepsis. Infection tends to rapidly overwhelm the immune system (NHS Antenatal and Newborn,2006) . Sickle-cell haemoglobin C is known to be milder, with symptoms related to vaso-occlusive crises resulting from higher hematocrit and blood viscosity. Obstructive crises cause sickle cell retinopathy is most common in older children, and this include renal necrosis, and aseptic necrosis of the femoral head (Belcher, 1993). The mildest of sickle-cell is the sickle-cell thalassaemia the individuals with this form of sickle-cell tend to be microcytic and hypochromic, which makes the cells less likely to clog the microcirculation even when sickling (Belcher, 1993). Severe hypoxia can be seen in individuals with the sickle cell trait and may cause vaso-occlusive episodes. The cells in these people form an ivy shape (Belcher, 1993). Recent studies have shown that stroke is co-exiting with Sickle cell disease. At least 1% of patients with sickle cell disorder suffer from stroke and those individuals result in physical disability, IQ reduction, Learning difficulties, TIAs and seizures (Beinz, 2007). Treatment of haemoglobinopathies. 10.1Treatment in Sickle-cell anemia. Febrile illness: Children with fever are screened (a full blood count, reticulocyte count and blood culture taken) for bacteremia. In young children the fever is treated with intravenous antibiotics, the children would be admitted at the hospital so that they can be monitored (Belcher, 1993).. But older children with reassuring white blood cell counts are managed at home with oral antibiotics, but if the older children have a history of bacteremia episodes, they get a hospital admission. (Modell et al, 2001) Zn administration: is when zinc is given to stabilize the cell membrane (Beinz, 2007). Painful (vaso-occlusive) crises: individuals with sickle cell disorder experiences painful episodes called vaso-occlusive crises. Vaso-occlusive crises is often treated symptomatically with analgesics (Beinz,2007). Pain management requires opioid administration at regular intervals until the crises has gone. The frequency, severity and duration of these crises episodes vary tremendously form episodes to episode or from person to person (Belcher,1993). Individuals who suffer from milder vaso-occlusive crises manage their pain on NSAIDs e.g. diclofenac or naproxen. And if the crises is severe, individuals require inpatient management, where intravenous opioids. Diphenhydramine is used to stop the itchiness associated with the opioids (Modell et al, 2001). Acute chest crises management is similar to vaso-occlusive crises treatment with the addition of antibiotics, oxygen supplementation for hypoxia, and close observation. If the pulmonary infiltrate worsen or the oxygen requirements increase,

Changing Feelings Towards Peter and Andrea in Once in a House on Fire E

Changing Feelings Towards Peter and Andrea in Once in a House on Fire 'Once in a house on fire' by Andrea Ashworth At the beginning of the Novel, A freak accident robbed Andrea of a loving father at the age of five. Her mother Lorraine, widowed at just twenty-five years old, was distraught, not least because she was left alone to raise Andrea and her younger sister Lauren ( also known as Laurie). By the time Andrea was six, she had a new 'father'... When the reader first meets Peter, it is difficult to contrive a clear opinion of him. He seems to show that he wants to be the children's "new daddy" by "lugging home bulging sacks of misshapen Mojos for my sister and I" He also appears to have a good relationship with his wife but we soon realise this is not so. A Jekyll and Hyde character, he swings between loving husband and father and violent, terrifying bully. Andrea would watch as her "mother smiled through his kissing compliments" but these soon turned into "vicious shouting matches which half the street could hear." The reader immediately feels anger towards Peter for his unjustifiable behaviour towards his family. But if you look at the quote, it is clear that it is a "match" which generally consists of two people or groups competing for supremacy. This shows that although Peter started the shouting, Andreas mother also played a part. This makes the reader feel annoyed. This is because although we feel that she should defend herself, she is contributing to the argument and therefore making it worse. Another incident showing how Lorraine contributed to an argument is when Peter comes home she has "got the kids cooking behind his back." and he is angry because he feels "she is lazing on her arse... ...What Peter has done is completely unexpected and brings out the Jekyll and Hyde element of his character. But for once, what he has done is neither loving nor hating. This reaction completely perplexes the reader. What this shows is that even though Peter is everything the reader thought in the first place, he is not as predictable and does not fit the stereotype. However this does not make the reader begin to like him but pity him even more. What is eventually clear is that although we do not think he intended it, Peter subconsciously started to, if not completely break the cycle he himself started. This is where the feelings of the reader can be divided. On one hand It could said this was just chance and it was Andrea who eventually broke the cycle or, it could also be said that they both played equal parts and eventually even Peter had, had enough.

Different Biomes

Our family always looks forward every vacation time because of so many places we visited and how we learned a lot from it.   It’s just like an educational tour.   As we traveled along we learned of different biomes in the world.   The world contains different kinds of Biomes.   Biome is a kind of large ecosystem where animals, insects, plants and human beings live in certain type of climate.   The following are some of the places we visited: 1.   Northern Alaska. In Northern Alaska, you will find their frosty biome called the Arctic Tundra.   The earth’s coldest Biome.   The Arctic tundra is a cold, vast, treeless area of low, swampy plains in the north around the Arctic Ocean.   An example of tundra is the Alpine Tundra that is at the tops of high mountains.   The type of climate affects plants and animals living on that area because of the availability of food supplies.   Examples of animals are the polar bears, arctic foxes and caribou.   Plants include the cushion plants, small shrubs and the lichen. 2.   Asia Tropical rainforests are found in Asia particularly along the equator.   It receives rains each year, approximately 70 inches.   Most of the species of plants and animals are found in this type of biome.   Many of its plants are used in medicines.   However, rainforests are considered an endangered biome because of the rapid growth of people who have cut the trees and contributed to the so called global warming.   Some of the animals of the tropical rainforest are the anteater, jaguar, brocket deer, lemur, orangutan, marmoset, macaw, parrot, sloth, and toucan. Among the many plant species are bamboo, banana trees, rubber trees, and cassava. 3.   Russia Taiga is the name of biome found in Russia.   It is a land dominated by conifers, like spruces and firs.   It has a limited variety of animals and plants compared to the temperate deciduous forest. References http://www.factmonster.com/ipka/A0769052.html                                             

Chemistry lab on saturated and unsaturated fats Essay

This experiment has also been trialled using KMnO4(aq) (0.0005 mol dm ) as the indicator. This turns from purple to colourless while unsaturation is still present. The procedure is the same as for bromine water, but portions of the potassium permanganate are added with swirling until the mixture fails to produce a colourless solution. The mixture requires more and more swirling as the amount of potassium permanganate increases. Warming fats in the Volasil using a beaker of hot water helps the fat dissolve and also speeds up the reaction. see more:chemistry matriculation This experiment should be done in a fume-cupboard with ready filled burettes. Background theory Saturation and unsaturation. Classic chemistry experiments 21 Safety Wear eye protection. Answers 1. Depends on what is supplied. 2. Weighing the fats and oils and calculating the exact amount of bromine water used per mole. 3. Unsaturated compounds contain double covalent bonds. Classic chemistry experiments Unsaturation in fats and oils Introduction Advertisements often refer to unsaturated fats and oils. This experiment gives a comparison of unsaturation in various oils. Burette  containing  bromine water Conical flask Oil and Volasil White tile What to record Volume of bromine water required for each oil. What to do 1. Using a teat pipette, add five drops of olive oil to 5 cm of Volasil in a conical flask. –3 2. Use a burette filled with a dilute solution of bromine water (0.02 mol dm ) (Harmful and irritant). Read the burette. 3. Run the bromine water slowly into the oil solution. Shake vigorously after each addition. The yellow colour of bromine disappears as bromine reacts with the oil. Continue adding bromine water to produce a permanent yellow colour. 4. Read the burette. Subtract to find the volume of bromine water needed in the titration. 5. Repeat the experiment with: five drops of cooking oil (vegetable) and five drops of cooking oil (animal). Safety Wear eye protection. Questions 1. Which sample is the most saturated and which is the most unsaturated? 2. This comparison is only approximate. How could the method be improved? 3. What does unsaturated mean?

Clostridium Difficle Infection In Health-Care Workers Essay Example

Clostridium Difficle Infection In Health Clostridium Difficle Infection In Health-Care Workers Essay Clostridium Difficle Infection In Health-Care Workers Essay Harmonizing to Bouza ( 2005 ) . Clostridium Difficile is a B that is gram positive and forms spores. Its chief manner of distribution is the environment whereby it besides colonizes 3-5 % of all healthy grownups without doing any symptoms that can be noticed. At babyhood. clostridia difficile colonizes between 2 % and 70 % . but the rates decrease with promotion in age and falling to approximately 6 % when the baby grows to two old ages. Above the age of two. the rate of clostridia difficile is much similar to that of an grownup. around 3 % ( APIC. 2008 ) . The strains responsible for the production of clostridia difficile are characterized by their ability in the production of both toxins A and B. The most common and rampant symptom of CDI is diarrhea that is non ever bloody. but can run from the soft and unformed stools to the watery and mucoid stools. Other outstanding symptoms include abdominal strivings and febrility and cramping in others. Clostridium difficile spores are extremely immune to devastation by most of the environmental agents and conditions. Their opposition can travel every bit far as defying some of the chemicals used in disinfection ( Zanotti-Cavazzoni. 165 ) . Therefore. this gives clostridia difficile the ability to last for months or longer in the environment and even in health care installations and the environing community. Chiefly. the spread of clostridia difficile is through the transportation of spores from a contaminated environment to the patient. or possibly through the custodies of wellness attention givers who do non follow proper hygiene and gloving patterns. The lone proper control step that can be adopted is the thorough disinfection and cleansing of the patient’s environment and besides through the physical remotion of the spores. In recent decennaries. there has been a recorded addition in the figure of reported rates of clostridia difficile-associated disease ( CDAD ) . There has besides been a recording in the addition in the figure of eruptions accompanied by terrible disease and besides an addition in mortality. The addition in CDAD is chiefly characterized by the followers ; alterations in the usage of antibiotics. a alteration in infection control patterns or the outgrowth of new strains of clostridia difficile that have increased virulency or antimicrobic. It is besides of import to grok the life rhythm of clostridia difficile in order to understand how to command it and if possible. prevent it. Its life rhythm begins in the spore signifier whereby they are because they are immune to heat. antibiotics or even acid. In a infirmary scene. clostridia difficile can be found in bedding. medical equipment. and furniture and on the health professionals. Upon consumption. the spores pass through to the bowels whereby they germinate and subsequently colonise the colon. Surveies have indicated that this bacteria colonized approximately 21 % of patients who are in the procedure of having antibiotics and at the same clip admitted to a general infirmary. Through the release of both toxins A and B. clostridia difficile subsequently induces diarrhoea and inflammatory bowel disease. However. the major hazard factors associated with clostridia difficile are advancement in age. hospitalization. and disinfectants. There are two major reservoirs of clostridia difficile in the health care puting. which are worlds ( symptomless and diagnostic ) and inanimate objects ( medical equipment and furniture ) . The degree of environmental taint depends chiefly on the badness of the disease of the patient. However the symptomless colonised patients should be regarded as the possible primary beginning of the taint. Clostridium difficile infection is more rampant among the aged in the society. The chief grounds for this are non to the full. but it can be attributed to the fact that the aged patients have a much less effectual barrier to infection. The importance of holding age as a hazard factor is characterized by the age distribution in lab studies as was received by CDSC during the research period of 1990-1992. Consequences showed that there was a prejudice for grownups over the age of 65 and they were more susceptible to holding terrible instances of clostridia difficile infections. There have besides been suggestions that clostridia difficile is endemic in installations that are considered long-stay for the aged. However. other surveies indicate that the difference in the endemic nature of clostridia difficile may be as a consequence of instance mix whereby patients are from other installations whereby the infection rate was high. Besides. clostridia difficile is endemic in many of the long -stay installations because the aged tend to remain longer in the ague wards than the other younger coevalss. Therefore. their increased hazard of infection is attributed to the increased exposure to antibiotics and nosocomial pathogens. There are several patient attention activities that provide a rife chance for the fecal-oral transmittal of clostridia difficile ( CDC ) . Such activities include ; sharing of electronic thermometers that have been used for mensurating rectal temperatures. unwritten attention or suctioning whereby the custodies or equipment have been contaminated. disposal of contaminated nutrient. medicine or with contaminated custodies and exigency processs like cannulation. Other factors like hapless manus hygiene. improper environmental and equipment cleansing and disinfection have besides been reported as a cause for infection and spreading of clostridia difficile. It has been rubber stamped that the environment is the major medium of distributing for clostridia difficile whereby it has been spread so widely that that it is impossible to indicate out a individual location that has non been contaminated. However. the environment of the septic patients is prevailing with clostridia difficile. for case. the lavatories. floors. sinks and linen. Despite disinfection. clostridia difficile spores are found to be longer than five months. Prevention and control of clostridia difficile is the duty of every person who is cognizant of its being. Therefore. bar steps must be endorsed by everyone. and particularly in attention giving installations whereby persons are more likely to distribute the infection. Standard safeguards refer to those patterns at work that are applied to every individual regardless of their confirmed or perceived infective position. Standard safeguards are the front line in the war against clostridia difficile. They help command the rate of infection from individual to individual. even in the most fecund hazard scenarios. They include ; manus hygiene before and after contact with the patient. the safe usage every bit good as disposal of sharps. the usage of protective equipment and the processing of reclaimable medical equipment. The proper handling of linen. safety in the direction of waste every bit good as sterile non-touch technique should besides be in the standard safeguards to be implemented in infirmary installations. However. when the first line of defence does non look to work expeditiously. there should be a backup program in topographic point. Therefore. when standard safeguards do non look to make the occupation. transmittal based safeguards should be implemented. These are extra work patterns for separately identifiable state of affairss that are put in topographic point to disrupt the transmittal of clostridia difficile. These safeguards are tailored to specific infections and their manner of transmittal. They include ; continued execution of standard safeguards. holding patient dedicated equipment. proper handling of equipment. enhanced cleansing and disinfection of the patient’s environment and the limitation of patients within the installations. Since health care scenes differ greatly in footings of their daily operation. it is difficult to come up with a direction proposal that would suit all installations. Therefore. all health care installations should carry on infection bar hazard appraisal on a regular footing alongside acceptance of elaborate protocols and procedures for infection control. In acute attention puting. personal protective equipment should be provided for nurses and visitants outside the room of a patient who has confirmed clostridia difficile infection. Healthcare givers should utilize baseball mitts and gowns in order to forestall farther spread of infection. Conducting effectual manus hygiene is necessary for restricting the spread of clostridia difficile. They should be performed often and with the undermentioned considerations ; should be performed utilizing the Four Moments of Hand Hygiene. should be performed at the point-of-care utilizing a dedicated staff sink or the usage of manus rubs that have been impregnated with disinfectants or intoxicant and soap. In acute attention puting. particularly where the aged are shacking proper attention has to be considered chiefly because they are more susceptible to infection ( Rupnik. 2007 ) . One such step of forestalling clostridia difficile infection is puting the suspected or confirmed patients with CDI in a confined room that has dedicated lavatories. sinks and personal equipment. Furthermore. there is small demand for particular intervention for linen in an ague scene for both confirmed and suspected patients. Linen for diagnostic and symptomless patients should be in the same manner. The dirty linen should be carefully. For illustration. it should be placed in a no-touch receptacle in order to avoid taint of both the environment and the individuals around. In instances of eruptions. everyday infection control steps are of sedate importance in order to forestall the spread of the clostridia difficile infection to patients who have non yet been affected. The antibiotic policies have to be monitored every bit good as their conformity in order to successfully command the spread of infection. Hand rinsing processs should be followed to the latter by any individual who is in contact with septic patients such as physicians. nurses. paramedical staff and pupils. Nurses present challenges in battling clostridia difficile eruptions particularly because of the necessity to make a plain environment for the patients. This means that they have to invariably look into in with the patients and hence they become invariably at hazard of infection themselves in proper safeguard is non taken. For patients in the aged ague attention wards. the milieus are besides tailored to guarantee a comfy stay in the infirmary. Therefore. their soft trappingss and carpeted floors provide a challenge in instances of eruptions. For cases like this. preventative methods of battling the spread of clostridia difficile have to be implemented. One such step that should be used during cleansing is steam. Although the heat does non kill the pathogen. it helps in the containment of its spread. Patients are besides susceptible to undertaking infection from the attention devices used in the infirmary. Such devices include electronic thermometers or glucose measuring devices. These devices are in changeless usage and may be used by a assortment of patients. These devices are with pathogens derived from organic structure fluids. Thus it is of import to hold steps in topographic point to sterilise these devices particularly more exhaustively in times of eruptions. Another piece of communal setup used in wards is the linen. vesture. uniforms. lab coats and isolation gowns. Because clostridia difficile is normally in the environment and can last for more than five months. these pieces of vesture are ever in contact and possible taints are likely ( Dubberke. 17 ) . However indirect contact of such vesture comes from bedpans. lavatories and sinks of patients who are either suspected or confirmed to be infected. The presence of dirty linen is besides an country of importance that should be looked into carefully. Because bed linen is in infirmaries and wards. they should be cleaned and sanitized before they can be issued to a different patient. In order to assist battle the spread of clostridia difficile. the CDC has come up with the Spaulding categorization system. which identifies three hazard degrees that are associated with surgical and medical instruments ( Michel. 1095 ) . These degrees are ; critical. semi-critical and noncritical. Critical points include acerate leafs. indwelling urinary catheters and endovenous catheters. These are the points that usually enter the unfertile tissue. the vascular tissue or through which blood flows. Based on one of the recognized sterilisation processs. the equipment has to be unfertile before perforating any tissue. Semi-critical points include thermometers. electric razors and chiropody equipment and they are as those that touch mucose or tegument which is non integral. They require punctilious cleansing and thenceforth followed by high-ranking disinfection. Disinfection is done utilizing a chemo autoclave agent that is approved by the FDA. In decision. clostridia difficile has been on the rise in recent decennaries and it is merely through proper bar and control measures that it can be. Since it can populate in an environment in spore signifier for up to five months. it poses a challenge in footings of containment. On the other manus. the aged are more susceptible to clostridium difficile chiefly because of their low unsusceptibility and their drawn-out stay in infirmaries. However. with proper attention. opportunities of eruptions can be kept at a lower limit and more lives can be through bar alternatively of remedies. Mentions DelmAÂ ©e. Michel. Clostridium Difficle Infection In Health-Care Workers. The Lancet 334. 8671 ( 1989 ) : 1095. Print. Dubberke. Erik. Strategies for bar of Clostridium difficile infection. Journal of Hospital Medicine 7. S3 ( 2012 ) : S14-S17. Print. Patient Cloth Chairs and Clostridium difficile Outbreak. American Journal of Infection Control 37. 5 ( 2009 ) : E102-E103. Print. Rupnik. Maja. Abstract book: Clostridium difficile: being. disease. control A ; bar. s. l. : [ Organizing commission ICDS ] . 2007. Print. Zanotti-Cavazzoni. S. l. . Analysis of an eruption of Clostridium difficile infection controlled with enhanced infection control measures. Yearbook of Critical Care Medicine 2010 ( 2010 ) : 164-166. Print. clostridium difficle. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention. 1 Mar. 2013. Web. 30 Apr. 2014. hypertext transfer protocol: //www. Center for Disease Control and Prevention. gov/HAI/organisms/cdiff/Cdiff_infect. hypertext markup language Beginning papers

Lexeme - Definition, Etymology and Examples

Lexeme s In linguistics, a lexeme is the fundamental unit of the lexicon (or word stock) of a language. Also known as a  lexical unit,  lexical item,  or  lexical word. In corpus linguistics, lexemes are commonly referred to as lemmas. A lexeme is oftenbut not alwaysan individual word (a simple lexeme or dictionary word, as its sometimes called). A single dictionary word (for example, talk) may have a number of inflectional forms or grammatical variants (in this example, talks, talked, talking). A multiword (or composite) lexeme is a lexeme made up of more than one orthographic  word, such as a phrasal verb (e.g., speak up;  pull through), an open compound (fire engine;  couch potato), or an idiom (throw in the towel;  give up the ghost). The way in which a lexeme can be used in a sentence is determined by its word class or grammatical category. Etymology From the Greek, word, speech Examples and Observations A lexeme is a unit of lexical meaning, which exists regardless of any inflectional endings it may have or the number of words it may contain. Thus, fibrillate, rain cats and dogs, and come in are all lexemes, as are elephant, jog, cholesterol, happiness, put up with, face the music, and hundreds of thousands of other meaningful items in English. The headwords in a dictionary are all lexemes.(David Crystal, The Cambridge Encyclopedia of the English Language, 2nd ed. Cambridge University Press, 2003) Specifications of Lexemes [A] lexeme is a linguistic item defined  by the following specifications, which make up what is called the lexical entry for this item: its sound form and its spelling (for languages with a written standard);the grammatical category of  the lexeme (noun,  intransitive verb, adjective, etc.);its inherent grammatical properties (for some languages, e.g. gender);the set of grammatical forms it may take, in particular, irregular forms;its lexical meaning.These specifications apply to both simple and composite lexemes.(Sebastian Là ¶bner,  Understanding Semantics. Routledge, 2013) The Meanings of Lexemes Definitions are an attempt to characterize  the meaning or sense of a lexeme and to distinguish the meaning of the lexeme concerned from the meanings of other lexemes in the same semantic field, for example, the elephant from other large mammals. There is  a sense in which a definition characterizes the potential meaning of a lexeme; the meaning only becomes precise  as it is actualized in a context. Since the division of the meaning of a lexeme into senses is based on the variation of meaning perceived  in different contexts, a tension exists in lexicography between the recognition of separate senses and the potentiality of meaning found in definitions. This may well account in large part for the divergence  between  similar-sized dictionaries in the number of senses recorded and in consequent differences of definition.(Howard Jackson and  Ã¢â‚¬Å½Etienne Zà © Amvela,  Words, Meaning and Vocabulary: An Introduction to Modern English Lexicology, 2nd ed. Continuum, 200 5) Invariable and Variable Lexemes In many cases, it makes no difference whether we take a syntactic or a lexical perspective. Lexemes such as the and and are invariable, i.e., there is only one word corresponding to each. Also invariable are lexemes like efficiently: although more efficiently is in some respects like harder, it is not a single word, but a sequence of two, and hence efficiently and more efficiently are not forms of a single lexeme. Variable lexemes, by contrast, are those which have two or more forms. Where we need to make clear that we are considering an item as a lexeme, not a word, we will represent it in bold italics. Hard, for example, represents the lexeme which has hard and harderand also hardestas its forms. Similarly are and is, along with be, been, being, etc., are forms of the lexeme be. . . . A variable lexeme is thus a word-sized lexical item considered in abstraction from grammatical properties that vary depending on the syntactic construction in which it appears.(Rodney Huddleston and G eoffroy Pullum, The Cambridge Grammar of the English Language. Cambridge University Press, 2002) Pronunciation: LECK-seem

30 English Words Borrowed from Dutch

30 English Words Borrowed from Dutch 30 English Words Borrowed from Dutch 30 English Words Borrowed from Dutch By Mark Nichol During much of the 1600s, the Netherlands was a world power, especially at sea, and this influence contributed to the English language in the form of borrowings from Dutch into English of various nautically and aquatically themed words. Here’s a list of many of these terms (a few of which were adopted from, or may derive from cognates in, other languages) and their definitions and their Dutch origins. 1. avast (â€Å"stop†): from hou vast, meaning â€Å"hold fast† 2. bow (â€Å"front of a ship†): from boeg (or from Old German or Old Norse) 3. brackish (â€Å"salty†): from brac (or a Low German cognate), meaning â€Å"salty† 4. buoy (â€Å"marker† or, as a verb, â€Å"mark with a buoy† or â€Å"keep afloat†): from buoy, ultimately from the Latin word boia, meaning â€Å"shackle† 5. caboose (â€Å"the last car on a freight train, used for the accommodation for the train’s crew†): from kabuis or kombuis, meaning â€Å"galley,† or â€Å"ship’s kitchen† 6. commodore (â€Å"senior captain† or â€Å"naval officer above a captain in rank†): probably from kommandeur, ultimately from the Old French word comandeor, meaning â€Å"commander† 7. cruiser (â€Å"warship larger than a destroyer but smaller than a battleship,† or â€Å"pleasure motorboat†): from kruisen (related to kruis, meaning â€Å"cross†), meaning â€Å"sail across or go through† 8. deck (â€Å"any of various floors of a ship†): from dek, meaning â€Å"covering† 9. dock (â€Å"mooring structure for vessels† or, as a verb â€Å"tie up at a dock†): from docke, meaning â€Å"pier† 10. dredge (â€Å"riverbed or seabed scoop† or, as a verb, â€Å"drag† or â€Å"scoop†): perhaps based on dregghe, meaning â€Å"dragnet† 11. freebooter (â€Å"pirate†): from vrijbuiter, meaning â€Å"robber†; the second half of the word is related to booty, also derived from Dutch 12. freight (â€Å"shipped goods† or, as a verb, â€Å"ship goods†): from a word variously spelled fraght, vracht, and vrecht and meaning â€Å"water transport†; the Dutch word is also the source of fraught, meaning â€Å"heavy† or â€Å"weighed down† 13. filibuster (â€Å"obstructive act† or, as a verb, â€Å"obstruct†): from vrijbuiter by way of the Spanish word filibuster (see freebooter above), which in turn comes from the French word flibustier 14. hoist (â€Å"lift† as a noun or a verb): from hijsen 15. jib (â€Å"spar†): from gijben, meaning â€Å"boom† 16. keel (â€Å"spine or structure projecting from a hull†): from kiel 17. keelhaul (â€Å"punish by dragging over the keel†): from kielhalen, meaning â€Å"keel hauling† 18. kill (â€Å"riverbed†): from kil 19. maelstrom (â€Å"whirlpool† or, by extension, â€Å"confused situation†): from maalstroom, meaning â€Å"grinding current† or â€Å"strong current† (the second element of the word is cognate with stream); possibly based on an Old Norse word 20. morass (â€Å"boggy or muddy ground† or, by extension, â€Å"complicated or confused situation†): from marasch, meaning â€Å"swamp,† partly based on the Old French word marais, meaning â€Å"marsh† 21. plug (â€Å"stopper† or, as a verb, â€Å"stop (a hole)†): from plugge, meaning â€Å"stopper† 22. school (â€Å"large group of fish,† unrelated to the term for an educational institution): from schole 23. scow (â€Å"small, wide sailboat† or â€Å"flat-bottomed boat†): from schouw 24. shoal (â€Å"large group of fish†; unrelated to the same word meaning â€Å"area of shallow water†): cognate with schole 25. skipper (â€Å"captain of a ship†): from schipper, meaning â€Å"someone who ships† 26. sloop (â€Å"sailboat,† either a small modern boat or a specific type of warship): from sloep, either ultimately from slupen, meaning â€Å"to glide,† or from the Old French term chalupe 27. smack (â€Å"small sailboat†): possibly from smak, meaning â€Å"sailboat,† perhaps from the sound made by flapping sails 28. smuggler (â€Å"illegal trader†): smokkelen or the Low German word smukkelen, meaning â€Å"transport (goods) illegally†) 29. stockfish (â€Å"cod or similar fish prepared by drying†): from stokvis, meaning â€Å"stick fish† 30. yacht (â€Å"small, light pirate-hunting naval vessel† or â€Å"pleasure motorboat or sailboat†): from jacht, meaning â€Å"hunt† and short for jachtschip Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Vocabulary category, check our popular posts, or choose a related post below:20 Words with More Than One SpellingItalicizing Foreign WordsForming the Comparative of One-syllable Adjectives

Total Quality Management (TQM) Research Paper Example | Topics and Well Written Essays - 750 words

Total Quality Management (TQM) - Research Paper Example What makes total quality management peculiar is the fact that brings on board the inputs of not just a limited component of the organization but the collective efforts of all stakeholders towards the success of the organization. Total quality management also tries to make the customer the central focus and attention for quality delivery. This means that the target for ensuring success is to ensure that the customer receives quality of service. Industry Adoption of TQM Today, it is said that the adoption of total quality management by industries is no longer a luxury but a responsibility (Ferreira & Otley, 2003). The reason for this is in the numerous benefits that the adoption of total quality management comes with. Though the benefits will be discussed into detail in subsequent sections, it can be said that the need for industries to adopt total quality management is mainly in the structure of their organizations. First, it can be asserted that for any given industry, there is the p rivileged of having a multi-structural organogram in place. An organogram may best be described as an organizational structure, which for industries is made up of several input stakeholders. All of these input stakeholders who may include shareholders, board of directors, management, employees and suppliers all have a responsibility of ensuring that the industry achieves its goals. Because of the divergent nature of the structure and because of the fact that total quality management deals with different stakeholders playing their roles, it becomes easier for industries to adopt total quality management. The other point is that there is the customer factor, where various industries have customers, whom they are expected to serve their interests. For this reason, it becomes necessary to adopt total quality management and use it to serve the purpose of the customer. Benefits of TQM Considering the face of change that is being associated with total quality management, the best benefit t hat can be assigned to total quality management is the fact that it helps in the creation of competitive advantage for various companies. Competitive advantage becomes necessary when virtually every other company is doing the same thing and performing at the same level (Ezzamel, 2004). For example when all competitors are charging the same service price, it becomes necessary to have a fighting force that would ensure that customers choose your company over others, though the prices may be the same. Today, there is much evidence to the fact that customer prefer customer satisfaction to cost salvaging. To this end, when total quality management is implemented to bring about customer satisfaction, it serves as a competitive advantage for the organization to win the hearts of customers. What is more, adopting total quality management ensures a coherent organizational atmosphere. This is because it puts every member of the working force at post and enshrines that each person plays his or her role judiciously (Rank, 2012). Hurdles to Quality Improvements The implementation of total quality management has often been faced with several hurdles and challenges, among which includes the fact that there has often been apathy and lack of cooperation from the entire workforce. The reason why this has

Communicating Across Organizational Boundaries Assignment

Communicating Across Organizational Boundaries - Assignment Example This paper, therefore, provides some of the considerations to be put into place when communicating with colleagues from this country. One of the communication aspects to recognize while in Baghdad is the religion or religious practices of Baghdad inhabitants. Islamic religion dominates almost all parts of the Middle East countries. It is, therefore, necessary to put into consideration the aspect of religious norms whenever you are communicating with colleagues from Baghdad. A Muslim as per the Koran is someone who has accepted Islamic religion and is willing to live his whole life in accordance to the Islamic teachings. It is also necessary to note that Islamic communication aspects are often unique. Therefore, they usually engage in the use of body language whenever they communicate (Emmitt & Gorse, 2003). Muslims believe in showing much respect to one another; therefore, shouting when talking should be totally avoided when engaging in an ordinary conversation with them. Islamic greeting cordially embroils the use of theological terms like â€Å"may peace of the lord be upon you or may God’s blessings be with you† (Hartig, 2011). It is, therefore, highly important to consider these aspects of salutations whenever you are communicating to a colleague from Baghdad. Cultural practices also play a significant role in communication. It is, therefore, necessary to consider Islamic cultural beliefs when communicating with a person from Baghdad. Some languages may be ordinarily used in other countries, but while in Baghdad, these languages are taboos and unpleasant to the ears of Baghdad’s inhabitants. Culture refers to a people’s way of life including their language practices, foods they eat, values and norms (Emmitt & Gorse, 2003). In most cases, Islamic communication aspect of culture is often upheld especially when communicating with elders. Most Muslims uphold a higher integrity of communication values that involve respect for the

Celestial Seasonings Tea Research Paper Example | Topics and Well Written Essays - 250 words

Celestial Seasonings Tea - Research Paper Example specialty tea market by exceeding consumer expectations with: The best tasting, 200% natural hot and iced teas, packaged with Celestial art and philosophy, creating the most valuable tea experience† (Stone 3). The values of beauty and truth are its viewpoint in order to produce the highest quality of specialty teas through the use of the botanical products. To ensure the financial stability of Celestial Seasonings, the company decided to merge with the Hain Food Group and become The Hain Celestial Group. The Hain is a market leader of natural food products and a successful distributor of organic foods and personal care products. The company has a market capitalization of $1.05 billion with total revenue of $917.34 million. The reported revenue for this year is lesser compared to the revenue of the previous years (â€Å"Income Statement†). However, the company’s operating income as well as the position of financial statements is performing well. Also, the stock price performance for this year under the ticker symbol HAIN is increasing with a closing rate of 24.48. Celestial Seasonings is having a â€Å"50-percent market share in the herbal tea segment and 32-percent of the total specialty tea category† (â€Å"The Hain†). The Hain Celestial Group competitors in share market are General Mills Inc., Kraft Foods Inc., Nestlà © and Processed & Packaged Goods (â€Å"Competitors†). In the field of herbal tea segment, its major competitors are Lipton Tea, Bigelow Tea, Luzianne Tea, Twinings and Tetley, and all of these companies are fighting over the tea sales in America. â€Å"The Hain Food Group to Merge with Tea-Maker Celestial Seasonings.† All Business. All Business.com, 13 Mar. 2000. Web. 4 Nov. 2010.

Field Experience #5 Policy Essay Example | Topics and Well Written Essays - 1000 words

Field Experience #5 Policy - Essay Example The challenges in evaluated are in a wider dimension linked to the interpretations in policies and guiding procedures for teacher evaluation. For effective evaluation, there is need to review the consistency of the policies with the state law to ascertain their legality and their entire separation from procedural requirements of teacher evaluation. From a general point of view, the policies are supposed to give guidance for procedures in the assessment to ensure legal consistency. A policy is simply a set of rules and principles which are used as a guide in decision making or procedural activities with the goals of the principles clearly stated. The teacher evaluation policy is part of Arizona’s education policies in which there are guidelines to teacher evaluation procedures. Policies are usually politically negotiated rules governing the entire operation of a system which in our case is teacher evaluation and must be consistent with the law. On the other hand teacher evaluation procedure is a set of guidelines agreed upon by professionals in the field on best practice in evaluating teachers for compliance to education policies. This might be the beginning of the trouble in understanding policy and procedural requirement of teacher evaluation because of some inconsistencies in the application of the two especially after the law changes in Arizona. In the Standards for Arizona Teachers we find more description of procedural activities in teacher evaluation and less of policy matters. It offers a criterion for judgment of good practice and indicators of teacher failure. As part of legislation we find the policies based on the old set of law on education but with the recent changes there is a lot that is inconsistent with the state law. Just to cite an example the law which is observed to discriminate against teachers whose first language is not English is contrary to what the policy covers under communication requirements of a teacher. In

Essay Example | Topics and Well Written Essays - 250 words - 178

Essay Example Media practices engross a course of communication between people, and such communicative processes shape societal behavior. This is evident in the materialistic role that cinema, as a form of technology, plays in the society. Larkin cites Nigeria as a country in which cinema creates a fantasy space that comprise the entire sensory experience of urban living and modernity (Larkin, 2002). Technological determinism changes the traditional structures of sociability. Michael Warner asserts that the cultural structure of a medium is a set of political conditions of discourse, such as practices and structured labor referred to as technology (Warner, 1990). News making in the digital era is guide by clicks and spins, as explained by Dominic Boyer (2013). The author explains the communicative process in the digital process from a perspective that sees the process as an unconscious way of reading the mood of the society, who is the object. Similarly, Amanda Weidman confirms that the association of class structures and technological media shape notions of power and realism by dictating which information circulates across the public (Weidman, 2010). Mediating technology and mediated content, which are the subject and object respectively, determine people’s listening practices and psychological

Is there a necessary connection between a philosopher's politics Essay

Is there a necessary connection between a philosopher's politics and their philosophy - Essay Example It should be noted that Heidegger was forced into the sidelines within only months of joining the party and despite the claims that his philosophy is compatible to Nazism, it actually went in the opposite direction. Heidegger’s philosophy was based on an attempt to understand Being, and to address it as a problem that philosophers throughout history had failed to address. He believed that an understanding of being was necessary to ensure that human beings were not only able to understand themselves, but the world around them as well.2 This is in complete contrast with Hitler’s and Nazi policies, which often concentrated on the promotion of the Aryan race as well as the development of social programs designed to destroy rather than to develop and understand. When compared to Heidegger’s philosophy, which advocated for the universality of the human race, the basis of the social programs promoted by the Nazi regime was to ensure that racial purity for the Aryan race was maintained at all costs. This is because it was believed that the German nation had become weak and would not be able to continue retaining its superior status if undesirable individuals were allowed to survive .3 One of the cruellest of these social policies was that of the forced sterilization of those individuals who were believed to be from lesser races and who carried any form of genetic weakness. In order to make this policy effective, laws were put in place to ensure that doctors provided all the information concerning their patients to the state so that the latter could be able to determine those individuals who had the desirable characteristics to ensure the creation of the German master race. A process where individuals could report others who they suspected of being genetically weak was made possible and this ensured that the Nazi government was able to get to as many people

Essay Example | Topics and Well Written Essays - 250 words - 178

Essay Example Media practices engross a course of communication between people, and such communicative processes shape societal behavior. This is evident in the materialistic role that cinema, as a form of technology, plays in the society. Larkin cites Nigeria as a country in which cinema creates a fantasy space that comprise the entire sensory experience of urban living and modernity (Larkin, 2002). Technological determinism changes the traditional structures of sociability. Michael Warner asserts that the cultural structure of a medium is a set of political conditions of discourse, such as practices and structured labor referred to as technology (Warner, 1990). News making in the digital era is guide by clicks and spins, as explained by Dominic Boyer (2013). The author explains the communicative process in the digital process from a perspective that sees the process as an unconscious way of reading the mood of the society, who is the object. Similarly, Amanda Weidman confirms that the association of class structures and technological media shape notions of power and realism by dictating which information circulates across the public (Weidman, 2010). Mediating technology and mediated content, which are the subject and object respectively, determine people’s listening practices and psychological

Communicable Diseases Essay Example for Free

Communicable Diseases Essay Improvement in the health status of the population has been one of the major thrust areas for the social development programmes of the country. This was to be achieved through improving the access to and utilization of Health, Family Welfare and Nutrition Services with special focus on under served and under privileged segment of population. Main responsibility of infrastructure and manpower building rests with the State Government supplemented by funds from the Central Government and external assistance. Major disease control programmes and the Family Welfare Programmes are funded by the Centre (some with assistance from external agencies) and are implemented through the State infrastructure. The food supplementation programmes for mothers and children are funded by the State and implemented through the ICDS infrastructure funded by the Central Government. Safe drinking water and environmental sanitation are essential pre-requisites for health. Initially these two activities were funded by the Health Department, but subsequently Dept. of Urban and Rural Development and Dept. of Environment fund these activities both in the State and Centre. Health and health care development has not been a priority of the Indian state. This is reflected in two significant facts. One, the low level of investment and allocation of resources to the health sector over the years about one percent of GDP with clear declining trends over the last decade. And second the uncontrolled and very rapid development of an unregulated private health sector, especially in the last two decades.This does not mean that there was no health policy all these years. At the state government level there is no evidence of any policy initiatives in the health sector. The Central government through the Council of Health and Family Welfare and various Committee recommendations has shaped health policy and planning in India. It has directed this through the Five Year Plans through which it executes its decisions. The entire approach has been program based. The Centre designs national programs and the states have to just accept them. The Centre assures this through the fiscal control it has in distribution of resources. So, essentially what is a state subject the Centre takes major decisions. However it is important to note that this Central control is largely over preventive and promotive programs like the Disease Control programs, MCH and Family Planning, which together account for between half and two-thirds of state budgets. Curative care, that is hospital and dispensaries, has not been an area of Central influence and in this domain investments have come mostly from the state’s own resources. Structured health policy making and health planning in India is not a post-independence phenomena. In fact, the most comprehensive health policy and plan document ever prepared in India was on the eve of Independence in 1946. Especially the 80% population residing in rural areas. It is only an embarrassment for the Indian nation that more than half a century later there is no evidence of development of health care services to an expected level. The enclave pattern of development of the health sector continues even today – the poor, the villagers, women and other underprivileged sections of society, in other words the majority, still do not have access to affordable basic health care of any credible quality. This Research Paper includes analysis of existing Health Planning and the development of health status of the society in the past decade 2001 to 2011 . Census of India 2001 and Census of India 2011 used. Decline of Fertility rate,Maternal Mortality rate ,Infant Mortality rate and other developments are studied .At the same time Upgrowing Trend of fatality of some communicable diseases (Dengue,Malaria,Cholera) and Noncommunicable Diseases (Heart Diseases,Diabetic ) are also studied and analysed in this paper. Key Words : Health planning,development,IMR,MMR,TFR,Upgrowing CDs and NCDsDiseases. Health planning and policies : Good health is a basic requirement for quality of life. It is the foundation for social and economic development. The objective of the government is to ensure that health care services are rendered, keeping in view the core principles of accessibility, equity, quality and affordability. This will be accomplished through strengthening of the health care network throughout the state to deliver not only curative but also preventive and rehabilitative care. To achieve the above objectives, the budget allocation of the Health and Family Welfare Department has been fixed at Rs 5569.28 crores for the financial year 2012-13 as against the provision of Rs.3889 crores for the year 2010-11 registering an increase of more than 40%. Tamil Nadu fares well on the health indicators which form a part of the Human Development Index (HDI) as compared to other Indian states.Government policy interventions and funding have played an important role in the State’s better health outcomes. Tamil Nadu has implemented various programmes with special focus on maternal and child health which has resulted in the reduction of vital indicators such as the Maternal Mortality Ratio (MMR), Infant Mortality Rate (IMR) and Total Fertility Rate (TFR). However, the state willcontinue its efforts to improve its performance in the health sector by benchmarking itself against higher targets. The recently released â€Å"Vision 2023â€Å" envisages Tamil Nadu to become not only the numero uno State in India in terms of social indicators, but also reach the levels attained by developed countries in human development by ensuring universal access to health facilities† This Government will continue to give prominence to the health of women and children. Promotion of institutional deliveries by strengthening the Primary Health Centres and Health Sub-Centres with qualified and trained manpower, establishment of upgraded Primary Health Centres in each block with 30 beds, an operation theatre and various other facilities, provision of 24 hours delivery care services by positioning 3 staff nurses in each Primary Health Centre, provision of emergency obstetric care in the CEmONC Centres established in the district and select taluk hospitals, ensuring availability of an Emergency Response System through 108 ambulances with inter facility transfer, provision of safe blood at the upgraded Primary Health Centres, provision of neo-natal ambulances for the transportation of neo-natal emergencies, establishment of Neo-natal Intensive Care Units (NICUs) with trained Doctors and Staff Nurses in each district are all schemes which would no doubt help to achieve go od progress in the further reduction of MMR and IMR, in the coming years. The benefit under the Dr.Muthulakshmi Reddy Maternity Benefit Assistance Scheme has been enhanced to Rs.12,000, which is the highest in the country. This has come as a boon to the poor beneficiaries who deliver in government health facilities. The three phase payment has also strengthened antenatal, postnatal care and improved child immunization. The scheme would have a major impact on further improving the maternal and child health indicators in the State. An allocation of Rs.720 crores has been provided for this scheme in 2012-2013. This Government has announced a path breaking new scheme for free distribution of sanitary napkins to rural adolescent girls. This scheme which has been launched by the Hon’ble Chief Minister on 27th March 2012, will benefit over 41 lakh adolescent girls in the 10-19 age group in rural areas covering all the districts of the state. Sanitary napkins will be distributed through schools and Anganwadis. This initiative will go a long way to improve personal hygiene, prevent future complications such as infertility and promote the health of the future mothers. An amount of Rs.55 crores has been provided for this scheme in this financial year. State-wide programmes have been launched for the management of iron deficiency anaemia and gestational diabetes. The State has been the first to introduce the use of injection iron sucrose in the public sector for reducing severe anaemia in pregnant women following a protocol developed by senior obstetricians and specialists. Addressing these major underlying causes will no doubt help to reduce maternal morbidity and mortality further. The Chief Minister’s Comprehensive Health Insurance Scheme has been launched on 11th January 2012 to provide insurance coverage for life threatening ailments to the poor people of Tamil Nadu. This scheme has enhanced the sum assured to rupees one lakh per year and Rs.4 lakhs for a period of four years and h as also extended the coverage to more diseases and included diagnostic procedures. Special provisions have also been incorporated to strengthen the role of Government hospitals in implementing the scheme. So far, 26,172 beneficiaries have undergone treatments costing Rs.70.53 crores. A sum of Rs.750 crores has been provided for the implementation of this scheme in 2012-2013. As new initiatives, during 2012-2013, the infrastructure for operation theatres in district and medical college hospitals will be improved at a cost of Rs.20 crores. Post-mortem facilities will be improved at a cost of Rs.10 crores. To improve the services available to the public, diagnostic equipment will be provided at a cost of Rs.10 crores and MRI facilities will be provided in 5 Medical Colleges through Public Private Partnership. The Burns centre in Kilpauk Medical College Hospital will be upgraded as a Centre of Excellence at a cost of Rs.5 crores. The incidence of cancer as a disease hasgradually been increasing and it has become a major cause of morbidity and mortality in the State. A State Cancer Registry to collect details of all the cancer cases in the State will be put in place fromthis year. Further, most forms of cancer are treatable if detected early. Seventy percent of various types of patients seek treatment in an advanced stage. There is only one exclusive cancer hospital in the Government sector i.e. Arignar Anna Cancer Hospital at Karapettai, Kancheepuram is providing treatment to the patients. Considering the increasing need for specialized cancer care, Government has decided to establish Regional Cancer Centres at the Government Rajaji Hospital, Madurai and Coimbatore Medical College Hospital at a cost of Rs.15 crores per centre. These cancer centres will address the needs of the cancer patients in the Southern and Western region of the State. A new programme to screen the high risk population for oral cancer and to diagnose it at an early stage will also be launched. The King Institute of Preventive Medicine and Research, Guindy, Chennai, is one of the premier institutions of this country. It is also a teaching and research centre. The Virology department of this Institute is recognized by Government of India and the World Health Organisation as the National Polio Laboratory. This institute was manufacturing vaccines and serum which was stopped some years back. It is now proposed to revive the vaccine production and create a Tissue bank in the KingInstitute of Preventive Medicine and Research, Guindy, Chennai, at a cost of Rs.5 crores. Special focus will be provided on non communicable diseases like diabetes, hypertension, cardiovascular diseases and cancer of breast and cervix which are emerging as major causes of morbidity and mortality. A two pronged strategy wil be adopted to tackle these diseases. While awareness creation for prevention through life style changes will be taken up at various levels, infrastructure facilities for early detection and treatment will be created. After the success of the pilot schemes in two districts, this activity has been scaled up to the entire State in phases. During phase -I, the programme has been taken up for implementation in 16 districts and during phase-II, the programme will be implemented in the remaining 16 Districts during the later part of the year. Rs.158 crores has been earmarked to the Health Systems Project for implementing the programmes during this year. Considering the growing urbanization of the State it is necessary to address urban health challenges, especially in small urban towns. 60 urban primary health centres already sanctioned under NRHM and the newly sanctioned 75 urban primary health centres have been brought under the control of Director of Public Health and Preventive Medicine. Strengthening of these centres with appointment of Medical Officers, Staff Nurses, ANMs, Pharmacists etc., is now taking place. The Medical Services Recruitment Board, which is the first of its kind in India, has been formed exclusively for the Health and Family Welfare Department to recruit candidates to fill up medical and para medic al vacancies in the Government Hospitals and Primary Health Centres. The Board is taking action to recruit candidates for ten major categories of posts which will no doubt improve the functioning of the government health institutions.The objective of Vision 2023 is to build a healthy society that will be able to take part in and share the fruits of economic development. The various schemes launched by this Government during the last year and the new schemes proposed now for this year would build a beginning to achieve the objectives of the Vision 2023. This includes Rs.5413.75 crores on the Revenue Account and Rs.154.62 crores on the Capital Account. The provision on the Revenue Account works out to 5.51% of the total Revenue Expenditure of Rs.98213.85 crores in the Tamil Nadu State Budget for the year 2012 -2013. Note: Apart from the above provision, funds towards Civil Works being undertaken by Public Works Department have been provided to the tune of Rs.323.68 crores under Demand No.39. The Directorate-wise provision for 2012-2013 made under Demand No.19 Health and Family Welfare Department is as follows: (Rupees in lakhs) Decadal Population growth rate as shown below : Current Status of Communicable Diseases in India India is undergoing an epidemiologic, demo-graphic and health transition. The expectancy of life has increased, with consequent rise in degenerative diseases of aging and life-styles. Nevertheless, communicable diseases are still dominant and constitute major public health issues. New viral and bacterial infections have been identified. Monitoring of anti-microbial resistance to commonly used drugs is being extended to include more organisms. Disease surveillance at the molecular level has been expanded and strengthened. Studies to assess disease burden not only in terms of morbidity and mortality but also economic are high on the Council’s agenda. Feasibility of effective strategies under field conditions for control of infectious diseases is being demonstrated. Research support to eradicate target diseases has been intensified. Development and evaluation of diagnostic tools, drugs and vaccines is being undertaken. Programme relevant research to strengthen the national health programmes and human resource development are an integral part of the efforts of the Council towards control of communicable diseases. It is evident that inspite of the declining mortality and changing morbidity pattern, India still has the â€Å"unfinished agenda† of combating the traditional infectious diseases that continue to contribute to a heavy disease burden and take a sizeable toll. Along with these, the country has to deal with the â€Å"emerging agenda† which includes chronic and newer diseases induced by the changing age structure, changing lifestyles and environmental pollution. We need to prepare ourselves to face the challenges of widening disparities between sections of the population in terms of access to good health. Till date, the diseases we have been able to eradicate in India are smallpox (in 1977) and guinea worm (in 2001) though we have many more in the agenda (polio, leprosy, yaws). Diseases like yaws and plague have been under control. During 1997, as many as 8515 cases of yaws were reported and treated. While during 2001, only 168 cases have been reported and treated4 i.e. 50 times reduction in four years time. Epidemics of cholera are not that frequent as in old days. Reported cases of cholera were 176,307 with 86,997 deaths in 1950.1 However, now total number of cases in a year is about 5,000 and mortality is also low. Dengue was predominantly an urban problem but now cases and outbreaks have been reported from rural areas also. There has been a decline in dengue fever/dengue hemorrhagic fever (DHF) incidence after 1996 outbreak in Delhi. However during 2001, outbreaks have been reported from Rajasthan, Tamil Nadu, Karnataka and Gujurat.4 Malaria is still a public health problem till today. The programme for eradication of malaria has been in place for the past 50 years under different names in our country. At the peak level of the success of programme in 1964, malaria was contained to less than 100,000 cases and no deaths. However, the situation slipped out of control and by 1976 we had 6,467,215 cases of malaria with 99 deaths.4 The total number of leprosy cases has dropped substantially from 2.91 million in 1981 to 0.44 million cases reported in March 2002. The prevalence rate has reduced from 57 per 10,000 in 1981 to 4.2 cases per 10,000 population in 2002. However, it is still much higher than the target, which is 1 case per 10,000 populations, of National Leprosy Elimination Programme. With these limited progresses, we have failed on many counts. Some diseases, which were once thought to have been conquered, have re-emerged in the recent years. Plague, which was a public health problem in the 1940s, speedily declined as a result of large scale application of dichlorodiphenyl- trichloroethane (DDT) in the year 1946.There was no laboratory confirmed plague in India during 1966 to 1993. However, during 1994, an outbreak of pneumonicplague was reported from Surat, Gujarat. Recently, in February 2002, an outbreak of plague was reported from Shimla, Tuberculosis : Tuberculosis accounts for a loss of approximately 11 million disability adjusted life years (DALYs). The burden of disease may increase further with the emergence of the HIV epidemic. The Revised National TB Control Programme (RNTCP) which covers more than 120 million population has successfully treated approximately 80% of patients in 48 districts of 16 states and Union Territories. Treatment success rates have more than doubled and death rates have decreased by 75 per cent. The ICMR’s Tuberculosis Research Centre (TRC) at Chennai is providing research support to the RNTCP through the conduct of basic, applied and operational research to develop better tools and training strategies for tuberculosis control. Diarrhoeal Diseases The National Institute of Cholera and Enteric Diseases (NICED), Calcutta and RMRC, Bhuban-eswar continued to pursue their research goals on different facets of diarrhoeal diseases. The NICED, Calcutta has earned an important affiliation with the Japanese International Collaborating Programme. Its active surveillance programme continues to monitor the newly emerging diarrhoeal pathogens Entamoeba histolytica,Rotavirus,Vibrio cholera and V.parahaemolyticus and addresses unknown frontiers in clinical diagnosis and disease management.A double-blind, randomized, controlled clinical trial was conducted by NICED,. These results suggest that zinc supplementation as an adjunct therapy to ORS has beneficial effects on the clinical course of dehydrating acute diarrhoea. Malaria The emergence of chloroquin resistance in P.falciparum and vector resistance to commonly used insecticides are the main obstacles in the control of malaria in the country. New technologies are being introduced for malaria control under Enhanced Malaria Control Programme. The roll back malaria programme has been launched simultaneously in all malaria endemic countries. These have thrown new challenges in malaria research. The Council’s institutes viz. Malaria Research Centre (MRC), Vector Control Research Centre (VCRC) and other institutes are making efforts to address these problems through focused research in vector and parasite biology and ecology, development of malaria control tools, drug development, testing and validation of new technologies. Disease Control Programmes – Non Communicable Diseases National Programme of Prevention Control of Cancer, Diabetes, Cardiovascular Diseases Stroke Programme (NPCDCS) . A new National Programme of Prevention Control of Cancer, Diabetes, and Cardiovascular Diseases Stroke (NPCDCS) was approved in July, 2010. This programme will cover 100 districts selected on the basis of their backwardness, inaccessibility and poor health indicators, spread over 21 States, during 2010-11 and 2011-12. The focus of the programme is on promotion of healthy life styles, early diagnosis and management of diabetes, hypertension, cardiovascular diseases and common cancers e.g. cervix cancer, breast cancer, and oral cancer and will cover about 200 million persons in all the districts. Conclusion: Our findings clearly establish the significant influence of the various Health planning studied on the health status of the society. They also show that this influence was more pronounced in the case of some health indicators maternal mortality rate,population growth rate, death rate, infant mortality rate than some communicable diseases survilance. The findings suggest that appropriate strategies and programmes need to be worked out to prevent CDs and control NCDs. especially to avoid upgrowing trend of some diseases like acute respiratory infection ,acute diarrhoeal disease,pulmonary tuberlosis , malaria,enteric fever , Pneumonia ect.. These would include awareness creation regarding sanitation more knowledge about the diseases and treatment and prevention through mass media and interpersonal channels. Healthy environment, especially safe drinking water supply, sanitary disposal of excreta and other wastes, and pollution-free housing and work places. Adequate nutrition, which in tu rn depends on production and availability, accessibility, affordability and intrafamilial distribution of food. Control over communicable disease. Lifestyle changes that influence the occurrence of non communicable diseases.The services of Government as well as non-governmental organizations could be sought for more effective implementation of such strategies and programmes. The management of the Health and family welfare programme at the grossroots level,which is likely to vary with the managerial skills of the programme manager, and its impact on the realization of the objectives of the health planning and programme . As management quality has been recognized as a critical factor in determining the success of Health planning implementation, staff recruitment and effective functioning of the PHC and sub-centres could be increased and thus the health plan could be more successful. 1.Associate Professor in Economics , Sri Parasakthi women College, Courtalam. 2. Research Scholar in Health economics , M.S.University, Tirunelveli. REFERENCES 1. Deodhar NS. Health situation in India: 2001.Voluntary Health Association of India. New Delhi. 2. Last JM. A dictionary of epidemiology. Third edition, Oxford University Press.1995. 3. GOI. National Health Policy 2002. Ministry of Health and Family Welfare, Government of India (GOI), New Delhi. 4. GOI. Annual Report 2001-2002. Ministry of Health and Family Welfare, Government of India (GOI), New Delhi. 5. World Health Organization 2002. Weekly Epidemiological Report. No 9:1st March 2002. 6. GOI. Combating HIV/AIDS in India 2000-2001. Ministry of Health and Family Welfare, National AIDS Control Organization. Government of India (GOI), New Delhi. 7. World Health Organization. NCD in South-East Asia region A profile WHO New Delhi 2002. 8. National Institute of Health and Family Welfare. National Health Programmes on Non Communicable Diseases, New Delhi. 2003. 9.http://www.who.int/. [Last assessed on 2012 July 31] 10. World Health Organization. Global Status Report on non-communicable diseases 2010. 11. Beaglehole et al. Priority actions for the non-communicable disease crises. THE LANCET 2011; 377:9775; 1438-1447. 12. World Health Organization. Non-communicable Diseases Country Profile 2011. 13. World Health Organization. Global Health Observatory, 2011. 14. World Health Organization, Regional Office for South-East Asia. Non-communicable Diseases in the South-East Asia Region: Situation and response 2011 15. Beaglehole R. Globalization and the Prevention and control of non-communicable disease: the neglected chronic diseases of adults. THE LANCET 2003; 362:9387; 903-908. 16. Nongkynrih B, Ratro B K, Pandav C S. Current Status of Communicable and Non-Communicable Diseases in India. Journal of The Association of Physicians of India 2004; 52; 118-123. 17. Ministry of Health and Family Welfare (2011). Rural Health Statistics in India. New Delhi: Ministry of Health and Family Welfare. 18. World Health Organization (WHO). World Health Statistics, 2012 19. Ministry of Health and Family Welfare, Government of India. National Rural Health Mission (NRHM) 20. Ministry of Health Family Welfare. NCD Section. [Last assessed on 2012 July 31] 21. Ministry of Health Family Welfare, Government of India.Journal of National Cancer Control Programme2012. 22. Ministry of Health Family Welfare, Government of India. National Tobacoo Cont rol Programme. 23. Directorate General of health Services, Ministry of Health and Family Welfare, Government of India. Operational guidelines for Prevention and Control of Cancer, Daibetes, CVD and Stroke (NPCDCS). 24. Ministry of Health Family Welfare, Government of India. Indian Public Health Standards. http://www.mohfw.nic.in/NRHM/iphs.htm. [Last assessed on 2012 July 31] 25. The World Bank, South Asia Human Development, Health Nutrition and Population. NCDs Policy Brief: India, 2011 26.Srivastava R K, Bachani D. Burden of NCDs, Policies and Programmes for Prevention and Control of NCDs in India. Indian Journal of Community Medicine 2011; 36: S7-12 27.Health and family welfare department Demand No .19 Policy note 2012-2013 Dr.Vijay Minister for Health